Comprehension/Understanding is the good habit built up over time which helps a man step back and see the guiding principles which he can use to make better decisions. The man who seeks Comprehension/Understanding has the habit of stepping back and exerting persistent effort to see the big picture of the logic of things, including cause and effect, and how they apply in his life and the decisions he needs to routinely make. 

The vice opposing Comprehension/Understanding can be described as Ignorance, a consistent unwillingness to apply one’s intellect and reason to gain wisdom and see the broader picture in particular circumstances and to apply broader principles to his decision making. The man who lacks Understanding sentences himself to a prison of Ignorance, leaving him continually unable to make good and prudent decisions in life for he refuses to understand cause and effect and makes bad choices he could have avoided.